This guide is meant to help leaders, managers, decision-makers, monitoring and evaluation (M&E) staff and other development practitioners navigate their organizations and development initiatives more effectively towards sustainable development impact. It provides ideas, theories and tools which will help practitioners to better: understand the context in which the development initiative/organization operates, and tailor managing for sustainable development impact (m4sdi) to this specific context; connect sustainable development-related goals to stakeholder perspectives and motivations; engage people meaningfully in the initiative/organization and create or maintain a learning environment; turn M&E into an effective instrument for strategic guidance towards sustainable development impact.